Updated May 2025
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The struggle of infertility can be an overwhelming challenge. Potential parents can face overwhelming stress as many try to conceive, only to be disappointed when the pregnancy test comes back negative…again.
“We have seen many couples struggle with the challenge of infertility. It is an intensely emotional and exhausting experience,” said Dr. Pat Chappell. “There are many safe and effective ways to treat infertility. We also provide compassionate, emotional support, which we realize is so important during this time.”
We understand—many of our patients have faced infertility, and we have worked with them to help them have strong, healthy babies.
We know that there is an emotional, physical and psychological toll that infertility can take on patients, and that’s why we strive to provide the highest level of care in a manner that cares for the whole patient, treating them as valued individuals and not just a cluster of symptoms.
If you’ve been struggling with infertility, please contact us to schedule an appointment.
In this article, we’ll take a closer look at common reasons for infertility, possible solutions and how to safeguard your mental health as you take this demanding, and sometimes overwhelming, journey.
How Common Is Infertility?
Did you know that 12 percent of American women between the ages of 15 and 44 have difficulty getting pregnant or carrying a pregnancy to term?
An estimated 10% to 15% of American couples are infertile. Of those, one-third is due to an issue with the man, another third is due to an issue with the woman, and the remaining third is due to a health problem with both the man and the woman. About 6.1 million American women have difficulty getting or staying pregnant.
For healthy patients in their 20s, there is a 25% to 30% chance that there will be a pregnancy during any menstrual cycle, but by age 40, that number decreases to less than 10%
Effective treatment for infertility centers around determining the exact cause of the infertility and then providing a tailored treatment plan.
What Are the Main Causes of Infertility?
There are several causes of infertility. These causes include:
- Ovulation difficulties
- Irregular menstrual periods
- Amenorrhea can be a sign of ovulation difficulties
One of the most common causes of infertility is polycystic ovarian syndrome (PCOS), where hormonal imbalances interfere with ovulation cycles.
Other causes of infertility include:
- Physical problems with the structure of the uterus
- Blocked fallopian tubes
- Fibroids
- Primary ovarian insufficiency, which occurs when the ovaries stop working before a woman is 40
- Male factors, such as low sperm count, can account for 40% of fertility issues.
We’ll work closely with you to determine if you have one of the common reasons for infertility.
For our patients, we represent the best of both worlds: we provide the individualized treatment you’d expect from a smaller practice with the advanced medicine you’d expect from a larger, university-based health system. We understand that you’re not a statistic; you’re an individual.
We know that you are not alone in your struggle, and we want to work with you to find an effective solution.
Common Solutions for Infertility
To treat infertility, it’s important to determine the underlying cause. For example, if fibroids are the problem, we will provide treatment to resolve them.
We want you to have hope: There have been promising developments in the treatment of infertility, and many women have successfully conceived.
“Fortunately, there are always new innovations in helping our patients conceive, and we want them to know that they are not alone,” said Dr. Pat Chappell.
We’ll take a closer look at some of these innovative treatments next.
4 Innovative Infertility Treatments
1. Infertility Treatments with Letrozole
Letrozole is for breast cancer treatment in postmenopausal women. It inhibits estrogen production, which in turn affects how the pituitary and hypothalamus function concerning ovulation.
Letrozole may be particularly effective in helping women with polycystic ovary syndrome (PCOS) conceive.
The pituitary gland produces a number of hormones that have a direct effect on ovulation. A healthy menstrual cycle is the result of several organs working in concert: the hypothalamus, pituitary gland, the ovaries and the endometrium.
The pituitary gland releases a luteinizing hormone (LH) and follicle-stimulating hormone (FSH) that “communicate” to the ovarian follicles when to release a mature egg. As a result, the ovaries do not release eggs. The ovaries may also release eggs that are not fully developed.
2. Treatment with Gonadotropins
These medicines help women who don’t ovulate regularly each month or ovulate before the egg has matured. It works with the pituitary gland by adjusting when a woman ovulates to ensure a mature ovum.
Some women may be treated with both letrozole and gonadotropins during in vitro fertilization.
3. Infertility Treatments with Clomid
This medication also works with the pituitary gland by inducing ovulation in women who do not develop an egg.
Treatment with Clomid improves the way the ovaries respond to the follicle-stimulating hormone (FSH), resulting in improved live-birth rates.
4. Innovative treatments for in vitro fertilization
There have also been several improvements with in vitro fertilization, including pre-implantation genetic screening and studies to determine if the endometrium will be receptive to embryo placement.
These methods improve oocyte quality. An oocyte is an ovarian cell that must undergo division in order to form an ovum, or a mature female reproductive cell.
Solutions for You at Our Clinics in Chapel Hill, NC and Durham, NC
Infertility is heartbreaking and is a challenge both physically and psychologically. We want you to know that we have helped patients successfully conceive for more than four decades, and we’re dedicated to helping you find a solution. Schedule an appointment with us so we can discuss your options.
What Factors Influence Fertility?
Age is one of the primary factors that influences infertility. Roughly one-third of those over 35 have struggled with it, and aging can also increase the risk of having a miscarriage.
Health habits can also have some impact. While they are not the sole factor, smoking, excessive alcohol use or weight issues —either a large weight gain or a severe weight loss — can all contribute to the inability to get pregnant.
In some cases, extreme emotional or physical stress can result in amenorrhea, the absence of periods.
Can Infertility Be Cured?
There isn’t a simple cure for infertility.
However, we utilize the latest treatments to ensure that those who want to conceive have the best prognosis possible.
At Chapel Hill OBGYN, we are always up to date on the latest breakthroughs with infertility treatments, and we’re able to provide the research-based sophistication of a university medical center with the “small-town feel” of a family practice where everyone knows your name.
We’ve successfully cared for generations of women and have helped them overcome the emotional and physical challenges of infertility with compassionate, evidence-based care. Contact us today if you are having difficulty getting pregnant.
How to Test if a Woman Is Infertile: Our Experts Weigh In
Trying to get pregnant can be a challenging journey that makes a huge impact on the lives of many couples. But do you know how to test if a woman is infertile? Do you know what our gynecologists in Chapel Hill use to determine the course of treatment?
We’ll examine these tests and procedures, as well as touch on some of the more common infertility treatments in Chapel Hill and Southpoint that we offer.
How to Test if a Woman Is Infertile: A Pathway to Answers
There are several methods and procedures we use to determine how to test if a woman is infertile. The following are some of the most common:
Medical History and Physical Examination
The first step in how to test if a woman is infertile is to gain a clear, effective, overall picture of her health and unique medical history.
We’ll ask about items such as:
- Menstrual patterns—including any irregular periods
- If there were any previous pregnancies
- Miscarriages
- Pre-existing conditions
- History of sexually transmitted infections
- Previous surgeries
We’ll then perform a physical exam to assess your reproductive organs, checking to see if there are any structural abnormalities.
A physical exam is also a chance for us to consider other conditions that could be affecting your fertility, such as:
- Lumps that could signal fibroids or ovarian tumors
- Endometriosis
- Pelvic inflammatory disease
Testing for Hormonal Imbalances
Often, hormonal imbalances hold the key to what may be causing fertility issues. When discovering how to test if a woman is infertile, our tests may include:
- Follicle-Stimulating Hormone (FSH) Test: This test evaluates the functioning of your ovaries by measuring FSH levels. High FSH levels might indicate a diminished ovarian reserve or menopause.
- Luteinizing Hormone (LH) Test: This test detects the LH surge that triggers ovulation. Accurate timing is crucial for this test to be effective.
- Estradiol Test: This test measures estrogen levels and assesses ovarian function. Estrogen plays a crucial role in preparing the uterus for pregnancy.
- Anti-Mullerian Hormone (AMH) Test: This test assesses your ovarian reserve and predicts the number of eggs remaining. It provides valuable insights into your fertility potential.
- Progesterone and Testosterone Blood Tests: These tests evaluate hormone levels during specific phases of your menstrual cycle. By analyzing progesterone and testosterone, we can gather valuable information about ovulation status and hormonal imbalances.
Ovulation Testing
Tracking ovulation is like uncovering the key to your fertility puzzle. By tracking ovulation and understanding the patterns of your menstrual cycle, we can gain valuable insights into your reproductive health. Here’s how ovulation testing contributes to how to test if a woman is infertile:
- Ovulation Predictor Kits (OPKs): These little wonders detect hormonal changes, such as the surge in luteinizing hormone (LH), which triggers ovulation. OPKs are easily accessible and can be used in the comfort of your own home.
- Basal Body Temperature Charting: This method involves tracking your daily temperature to detect subtle increases indicating ovulation. It’s as simple as recording your temperature each morning before hopping out of bed.
Imaging Tests
We also utilize the latest technology for imaging tests that can provide insight into how to test if a woman is infertile. Some of these tests include:
Transvaginal Ultrasound
This is a valuable imaging test that can provide important information about your reproductive health and potentially uncover factors contributing to infertility.
During a transvaginal ultrasound, a small wand-shaped device called a transducer is inserted into the vagina, allowing for a close-up view of the uterus, fallopian tubes, and ovaries.
This procedure helps detect structural abnormalities that can interfere with your fertility. These abnormalities may include:
- Ovarian cysts
- Uterine fibroids
- Polyps
- Issues with the uterine lining
Hysterosalpingography (HSG)
Hysterosalpingography (HSG) is another way of how to test if a woman is infertile. This procedure involves injecting a contrast dye into the uterus while simultaneously taking X-ray images. The dye allows us to clearly see your uterus and fallopian tubes. This way we can check to see if the tubes are blocked or if you have scar tissue that may affect fertility.
Sonohysterography
Sonohysterography, also known as saline infusion sonography, is a specialized ultrasound procedure that can help diagnose infertility.
During this test, a small amount of sterile saline is injected into your uterus, allowing for a clearer visualization of the uterine cavity. This enables us to examine the thickness of your uterine lining. In addition, this can provide information about conditions such as polyps or fibroids.
Laparoscopy
During a laparoscopy, a thin, lighted instrument called a laparoscope is inserted through a small incision in the abdomen. This allows the surgeon to view the pelvic organs, including the uterus, fallopian tubes, and ovaries, directly.
Here’s how laparoscopy can aid in how to test if a woman is infertile:
- It can detect structural abnormalities
- It can help us discover problems with the fallopian tubes
- It can diagnose conditions such as endometriosis
The infertility treatment that’s right for you depends upon a number of factors, including the specific cause of your infertility. We’ll work with you to discuss the benefits and success rates of each treatment. Talking to one of our fertility specialists is key to helping us determine the best approach; we’ll tailor a plan suited just for you.
Ready to Take the Next Step in Your Dream of Starting a Family? Our Infertility Specialists in Chapel Hill Can Help
Our compassionate team of experts is dedicated to providing exceptional care and support for individuals and couples facing infertility challenges. With our state-of-the-art facilities and advanced fertility treatment options, we are committed to helping you navigate the path to parenthood.
Our caring team is ready to listen, understand, and provide you with the best possible solutions. Let us be your partner in the journey toward parenthood. Contact us for an appointment today.
Infertility is much more than a physical challenge; it creates intense emotions that can dramatically affect mental health. Next, we’ll explore the interaction of infertility and mental health as well as provide some useful coping strategies to help you.
Coping With the Struggle of Infertility and Mental Health
Every time you check your pregnancy test, you hold your breath. Your heart races.
Will you be met with joy or disappointment? And if the test is negative, will your disappointment cause you to spiral into depression?
Infertility and mental health can profoundly impact individuals and couples, triggering a range of emotions and challenges. It is something that has a dynamic impact on your journey.
Therefore, we’ll take a closer examination of the psychological effects of infertility and mental health, the significance of seeking support and the importance of self-care.
Understanding the Impact of Infertility and Mental Health
Infertility often leads to a complex array of feelings, affecting women both emotionally and psychologically. It’s not uncommon to experience emotions such as:
- Grief
- Depression
- Anxiety
- Hopelessness
- Extensive stress
To make matters more complicated, those dealing with infertility and mental health may face societal and cultural pressures to have a family. Even being around young children can cause deep emotional pain.
We have seen firsthand the dramatic impact infertility has on our patients. Therefore, we want you to know that we care about every aspect of your health, including your mental health.
Please come to us with any concerns, particularly if your intense emotions make it difficult to complete day-to-day tasks. We can provide resources and information on where to find licensed counselors and therapists who can help.
We want you to know that you have our support, so we’ve compiled this list of items that can provide assistance. These are crucial elements if you’re struggling with your mental wellness.
Healthy Ways to Cope With the Emotional Stress of Infertility
Having a Support System is Crucial
A support system is vital to help you as you face the exhausting and heartbreaking struggle of infertility. Important members of your support system may include:
- Friends
- Loved ones
- Family
- A therapist or professional counselor
- A member of the clergy
- Support groups
- Your health care team at Chapel Hill OBGYN
Infertility can be an isolating experience, and reaching out to an understanding friend, loved one, or family member can help improve your mental health.
When you share your feelings with those who truly care about you, they can help validate your emotions. Be honest about your struggles with infertility and mental health. This goes a long way toward alleviating feelings of isolation and self-doubt.
Practical Support Is Also Needed
While we’ve focused on the benefits of emotional support, there is also a need for practical support. Infertility treatments and appointments can be physically and mentally exhausting.
Don’t be afraid to ask your loved ones for help. They can help in many ways, including:
- Assisting with household chores
- Running errands
- Taking you to medical appointments
- Cooking meals
This will give you the space and time to focus on your well-being.
Online Support Groups for Infertility and Mental Health
There is also a world of online infertility support groups that provide a safe space to share experiences, connect with others who understand and find solace in a community of individuals going through similar struggles.
These can provide a safe space to talk about infertility and mental health.
Prioritizing mental well-being is paramount while navigating the challenges of infertility. Implementing self-care practices can provide a sense of empowerment and improve overall mental health.
Mindfulness and Meditation
These practices involve techniques involving:
- Cultivating awareness of the present moment
- Non-judgmental observations of thoughts and emotions
- Deep relaxation
Moreover, mindfulness and meditation enhance emotional resilience, fostering a greater capacity to cope with the challenges of infertility.
By grounding yourself in the present moment and practicing self-compassion, you can cultivate a more positive mindset, improved overall well-being, and greater acceptance on your journey towards parenthood.
Be Gentle With Yourself
Setting realistic goals and practicing self-compassion are vital aspects of the journey. Give yourself permission to cry and be angry. Don’t try to shut off your feelings. Give your spouse/partner permission to feel and cope differently than you.
Communicate Openly and Honestly with Your Partner
Open and honest communication with your partner is paramount when facing the challenges of infertility. By sharing your thoughts, fears, and emotions, you create a safe space for understanding and support.
We suggest:
- Talking openly about your experiences
- Giving each other time to express concerns
- Recognizing that your partner may be experiencing emotions that are different from yours
- Expressing your needs to each other
- Allowing room for deeper connection and empathy
- Listening actively to your partner’s perspective
- Providing reassurance
Together, you can navigate the ups and downs of the infertility journey as a team, making decisions and seeking appropriate support.
Engage in Activities that Bring You Joy
Sometimes, doing something you enjoy can help reduce stress. Engaging in activities that bring you joy is vital when coping with infertility and mental health.
Infertility can be emotionally draining, and it’s essential to carve out time for activities that uplift your spirits and bring a sense of happiness. You may consider:
- Learning a new hobby
- Spending time in nature
- Enjoying listening to music or playing a musical instrument
- Making time for a hobby you used to enjoy
- Taking a walk or going to an exercise class
Consider the Benefits of Professional Therapy or Counseling
Remember that there are therapists who specialize in helping those who are struggling with infertility. Therapists can provide a safe space for you to talk about your challenges, struggles and anxieties.
Evaluate How You Navigate Relationships and Social Situations
Remember that you may have to tell people what you need. In many cases, what someone thinks will help may not.
If you need to pass up the family gathering that features five nieces and nephews under two, then say so. If you want to be hugged, massaged, or left alone for a few minutes, or just listened to without any response, you’ll be more likely to get what you want if you ask.
Communicating with friends and family about infertility is essential, helping them understand the sensitivities involved and offering support.
Managing social situations, particularly pregnancy announcements, can be emotionally challenging, so don’t forget to reach out to your support system or therapist if needed.
We’ll Help You Through The Challenges of Infertility and Mental Health
Navigating the intersection of infertility and mental health is a difficult journey. By understanding the emotional impact, seeking support, practicing self-care, and fostering healthy relationships, you can help take care of yourself and your partner.
Remember, it’s essential to prioritize mental health and seek professional guidance when needed.
Chapel Hill OBGYN: Guiding You on Your Path to Parenthood
At Chapel Hill OBGYN, we understand the emotional and physical toll infertility can take on women and couples. That’s why we offer a range of specialized services tailored to meet your unique needs.
Our team of experienced and compassionate professionals is dedicated to providing the highest quality care, combining the latest advancements in reproductive medicine with personalized attention and support.
We offer:
- Initial consultations
- Fertility evaluations
- Infertility treatment options
- Comprehensive diagnostic tests
- Customized treatment plans that are appropriate for your medical history
We have helped hundreds of women conceive and go on to give birth to healthy babies. If you’re struggling with infertility, please reach out and schedule an appointment.
Key Takeaways:
- Infertility may be more common than you realize: It affects around 10% to 15% of American couples.
- There are several common causes of infertility. These include issues such as:
- Age (It’s easier for younger women to get pregnant)
- PCOS
- Fibroids
- Blocked fallopian tubes
- Lifestyle factors, which include
- Smoking
- Alcohol use
- Extreme stress
- Significant weight changes, either gaining or losing weight
- In certain cases, infertility may be caused by an issue with the man’s sperm count or other health issues.
- Treatments include:
- Letrozole
- Gonadotropins
- Clomid
- IVF
- Mental health support is vital; infertility can be an emotionally challenging and exhausting experience.
The content within this article and others on this website is only for educational purposes and should not be considered as medical advice. For any questions or concerns, please consult with your healthcare provider.
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Sources:
Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Eggs. Available from: https://www.ncbi.nlm.nih.gov/books/NBK26842/
Centers for Disease Control, “FastStats:Infertility,” https://www.cdc.gov/nchs/fastats/infertility.htm
Mayo Clinic. “Infertility: Its Symptoms and Its Causes.” Online https://www.mayoclinic.org/diseases-conditions/infertility/symptoms-causes/syc-20354317
Mayo Clinic“Meditation: A Fast, Simple Way to Reduce Stress,” https://www.mayoclinic.org/tests-procedures/meditation/in-depth/meditation/art-20045858
National Institute of Health, “New Treatment Increases Pregnancy Rate in Women With Infertility Disorder,” https://www.nih.gov/news-events/news-releases/new-treatment-increases-pregnancy-rate-women-infertility-disorder
Nedresky D, Singh G. Physiology, Luteinizing Hormone. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539692/
U.S. Office on Women’s Health, https://www.womenshealth.gov/